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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPF
All Species:
15.76
Human Site:
S495
Identified Species:
28.89
UniProt:
P49454
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49454
NP_057427.3
3210
367764
S495
N
N
L
L
K
S
H
S
E
Q
K
A
R
E
V
Chimpanzee
Pan troglodytes
XP_001171549
3114
357698
S495
N
N
L
L
K
S
Q
S
E
Q
K
A
R
E
V
Rhesus Macaque
Macaca mulatta
XP_001105956
3113
357422
S495
N
N
L
L
K
S
Q
S
E
Q
K
A
R
E
V
Dog
Lupus familis
XP_852813
1449
166096
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510329
2965
340022
T491
K
D
I
L
R
N
Q
T
D
Q
K
E
R
E
V
Chicken
Gallus gallus
O42184
1433
161009
Frog
Xenopus laevis
P85120
2058
236320
Zebra Danio
Brachydanio rerio
XP_002665261
2708
311087
S327
K
D
K
L
L
N
K
S
R
D
E
L
T
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
Honey Bee
Apis mellifera
XP_001120388
2064
240016
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
Sea Urchin
Strong. purpuratus
XP_796801
3636
416057
T492
K
E
G
L
V
F
K
T
E
Q
S
D
C
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25386
1790
206434
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
91.4
32.8
N.A.
N.A.
N.A.
N.A.
50.5
20.4
21.5
31.3
N.A.
21.3
22.9
20.1
22
Protein Similarity:
100
96.4
93.8
39.1
N.A.
N.A.
N.A.
N.A.
67.5
32.4
38.6
51.2
N.A.
35.2
41.3
36.4
43.7
P-Site Identity:
100
93.3
93.3
0
N.A.
N.A.
N.A.
N.A.
40
0
0
13.3
N.A.
0
0
0
26.6
P-Site Similarity:
100
93.3
93.3
0
N.A.
N.A.
N.A.
N.A.
80
0
0
40
N.A.
0
0
0
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
24
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
16
0
0
0
0
0
0
8
8
0
8
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
31
0
8
8
0
31
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
24
0
8
0
24
0
16
0
0
0
31
0
0
16
0
% K
% Leu:
0
0
24
47
8
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
24
24
0
0
0
16
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
24
0
0
39
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
8
0
0
0
31
0
0
% R
% Ser:
0
0
0
0
0
24
0
31
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
16
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
39
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _